Washington at Pittsburgh 6:40 PM ET
Pittsburgh ace Paul Skenes is coming off a career-worst start and will try to get himself and the Pirates back on track when they host the Washington Nationals in the first of a four-game series on Monday night.
San Francisco at Philadelphia 6:45 PM ET
Jung Hoo Lee and the San Francisco Giants hope to build off a productive weekend when they kick off a four-game series Monday against the host Philadelphia Phillies.
Boston at Tampa Bay 7:05 PM ET
Hitting the midway point of a four-series homestand, the Tampa Bay Rays play host to the visiting Boston Red Sox for the first of a three-game set on Monday.
Kansas City at NY Yankees 7:05 PM ET
Over six months ago, the New York Yankees beat the Kansas City Royals in a competitive four-game division series en route to their first World Series appearance since 2009.
Atlanta at Toronto 7:07 PM ET
Toronto Blue Jays left-hander Easton Lucas is scheduled to put his unblemished record on the line Monday night against the visiting Atlanta Braves.
NY Mets at Minnesota 7:40 PM ET
Clay Holmes' career shift has produced mostly positive results.
Detroit at Milwaukee 7:40 PM ET
After dropping the final two games of a western swing, the Milwaukee Brewers will look to bounce back behind left-hander Tyler Alexander when they return home to open a three-game series against the Detroit Tigers on Monday.
Houston at St. Louis 7:45 PM ET
With their rotation beset by injuries, the Houston Astros need left-hander Framber Valdez to be their stopper.
Chi. Cubs at San Diego 9:40 PM ET
The San Diego Padres are accomplishing feats that are rare in MLB history.
Colorado at LA Dodgers 10:10 PM ET
The Los Angeles Dodgers started the 2025 season with a surge, sweeping their first three series to build an 8-0 record.