Pittsburgh at Baltimore 6:35 PM ET
The Pittsburgh Pirates and Baltimore Orioles have gone through similar seasons, including manager changes this year.
Kansas City at Cleveland 6:40 PM ET
Things couldn't have gone much worse for the Kansas City Royals in the opener of a four-game series against the host Cleveland Guardians.
Washington at Miami 6:40 PM ET
A day after matching their best offensive performance of the season, the visiting Washington Nationals hope their late-season momentum carries into a series win against the reeling Miami Marlins on Tuesday.
NY Mets at Philadelphia 6:45 PM ET
The New York Mets are rapidly running out of chances to gain ground on the Philadelphia Phillies.
Detroit at NY Yankees 7:05 PM ET
In the opening weeks of the season, the New York Yankees visited the Detroit Tigers in frigid conditions.
Houston at Toronto 7:07 PM ET
Division leaders with diminishing leads clash Tuesday night when the Houston Astros visit the Toronto Blue Jays for the opener of a three-game series.
Chi. Cubs at Atlanta 7:15 PM ET
Chicago Cubs right-hander Cade Horton, who didn't give up a hit in his last start against Atlanta, gets another shot on Tuesday when the visiting Cubs face the Braves in the second game of their three-game series.
Tampa Bay at Chi. White Sox 7:40 PM ET
The Tampa Bay Rays need both self-help and outside assistance to improve their flickering American League wild-card hopes.
Milwaukee at Texas 8:05 PM ET
The Texas Rangers will look to continue their unlikely ascent in the American League playoff race as they pursue a series win over the major leagues' top team, the Milwaukee Brewers.
Minnesota at LA Angels 9:38 PM ET
The Minnesota Twins never quite recovered from a poor start to the season, but manager Rocco Baldelli is still paying close attention to how they finish.
Cincinnati at San Diego 9:40 PM ET
Michael King acknowledged he rushed his comeback last month from a nerve issue that caused problems with his pitching shoulder, leading to knee inflammation that landed him on the injured list for another month.
St. Louis at Seattle 9:40 PM ET
Riley O'Brien realized a dream in 2022 when he made one appearance for his hometown Seattle Mariners.
Arizona at San Francisco 9:45 PM ET
Two of the top 10 winners in the history of the Diamondbacks will meet head-to-head for the first time when Zac Gallen and Robbie Ray duel in the continuation of a three-game series between Arizona and the host San Francisco Giants on Tuesday night.
Boston at Athletics 10:05 PM ET
It's typically a winning day at the ballpark for the Boston Red Sox if Trevor Story hits a homer.
Colorado at LA Dodgers 10:10 PM ET
Intent on expanding their one-game lead in the National League West, the Los Angeles Dodgers are confident their starting staff and a cluster of returning players can help lead the charge down the stretch.